Therna partners with leaders across technology, life sciences, and research to accelerate the design, validation, and translation of programmable RNA medicines.
Partnering Initiatives
Therna partners with biopharmaceutical and life science organizations to apply its biology-guided, AI-driven platform to complex RNA challenges – advancing both therapeutic programs and foundational research.
Therapeutic Development
Therna collaborates with biopharmaceutical partners to design and develop RNA medicines across a range of modalities and disease areas, applying AI-enabled RNA design and experimental validation to accelerate therapeutic development from concept through preclinical and clinical readiness, including:
- ASO/siRNA design optimization and development
- mRNA optimization for CRISPR/Cas
- mRNA optimization for in-vivo CAR
- mRNA optimization for vaccines
- Increased protein titer for production lines
NVIDIA
Therna is partnering with NVIDIA, a leader in accelerated computing, to develop advanced AI models for programmable RNA therapeutics. The collaboration combines Therna’s proprietary experimental datasets from its RNA biology platform with NVIDIA CodonFM, a foundational model for RNA design, to enable more accurate representation of how mRNA sequences behave in cells.
Charles River
Therna collaborates with Charles River to advance single-patient RNA medicines for individuals with severe, ultra-rare disorders, combining AI-enabled RNA design with industry-leading preclinical development. Through this partnership, Therna and Charles River aim to accelerate the path from diagnosis to treatment by translating highly individualized RNA therapeutics into validated preclinical programs with the potential to become medicines.
PRESS RELEASE
University of Pennsylvania
Therna formed a scientific collaboration with the University of Pennsylvania and Dr. Hamideh Parhiz’s laboratory to advance mRNA delivery technologies to further strengthen Therna’s capabilities across design, evaluation, and translational development.
PRESS RELEASE
